Date of Award
Doctor of Philosophy (PhD)
Health & Physical Education
Syed M. Shah
Juma Al Kaabi
The United Arab Emirates (UAE) has one of the highest rates of type 2 diabetes mellitus in the world. Prior to the onset of type 2 diabetes mellitus, a period of moderate hyperglycemia is often present, referred to as prediabetes. This is associated with a significant loss of pancreatic beta cells, an increased risk of cardiovascular disease and other serious health issues. There are gaps in the literature concerning the prevalence of prediabetes and its associated correlates, as well as correlations between the conversion rates from prediabetes to type 2 diabetes mellitus. The primary objective of this study was to determine the prevalence of prediabetes and its correlates in adults. The secondary objective was to identify the proportion of conversions of prediabetes to type 2 diabetes mellitus and the major correlates.
This research was based on secondary data collected during prediabetes interventions in Al Ain and Dubai, two cities in the UAE. In Al Ain, a random sample (n=605) of parents participated in type 2 diabetes mellitus screening in a family-based study. In Dubai, 700 Emirati adults diagnosed with prediabetes, at five primary health care centers, were invited to take part in the intervention study. After ethical approval and gaining informed consent, socio-demographic, anthropometric, lifestyle and clinical data were then collected. Prediabetes and type 2 diabetes mellitus were defined in accordance with the American Diabetes Association’s guidelines: based on fasting plasma glucose (FPG ≥126 mg/dl (≥7 mmol/l) for type 2 diabetes, 110-125 mg/dl (6.1- 7 mmol/l) for prediabetes, (HbA1c ≥6.5%) for type 2 diabetes and (HbA1c 5.7-6.4%) for prediabetes.
We used a multivariable multinomial logistic regression analysis to identify the independent correlates for prediabetes and type 2 diabetes mellitus in comparison to people with normal glucose levels in Al Ain. In Dubai we used logistic regression analysis to identify the correlates of the transition from prediabetes to DM in the data from the various health centers. The overall prevalence of prediabetes and type 2 diabetes mellitus was 37.7% and 18.7%, respectively, in Al Ain. Ageing, being overweight and obesity were positive correlates for prediabetes. A secondary school, or higher, level of education correlated \negatively for prediabetes. Ageing, obesity, central obesity, a lack of vigorous physical activity and a family history of diabetes were positively correlated for diabetes, while a secondary school, or higher, level of education, were negative correlates for diabetes.
In Dubai, a significant proportion (23%) of participants with prediabetes suffered from DM within a two-year period. Low HDL-cholesterol was significantly (
Ali Al Marzooqi, Layla Mohamed Hassan, "Prevalence, Characteristics and Correlates of Prediabetes in Al Ain and Dubai, the UAE: Cross Sectional Study" (2018). Health and Physical Education Dissertations. 1.